Clinical Trial

Inflammatory Mediators as Potential Non-Invasive Biomarkers in Subjects With Eosinophilic Esophagitis

Active, Not Recruiting
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Summary
The investigators seek to assess esophageal inflammation or lack of it in response to treatment with a novel non-invasive method that would measure eosinophil-associated inflammatory mediators in the blood and urine to determine the presence of active Eosinophilic Esophagitis. For these purposes, the investigators will correlate esophageal inflammatory mediators measured in blood and urine with histological findings identified on esophageal mucosal biopsies. Additionally, biopsies associated mediators will be assessed relative to clinical phenotype and outcome.
Trial Details
NCT Number NCT03822325
Lead Sponsor Ann & Robert H Lurie Children's Hospital of Chicago
Conditions Eosinophilic Esophagitis
Enrollment 88 participants
Start Date 2011-02
Primary Completion 2015-05 (estimated)
Study Completion 2027-11 (estimated)
Updated on ClinicalTrials.gov 2026-06-05