Post Operative Cognitive Dysfunction After Breast Surgery

Aim of this trial is to define if Post-Operative Cognitive Dysfunction, detected analyzing changes between pre-operative and post-operative Neurocognitive Test, and Postoperative Delirium, relate to concentration of effector's site concentration of propofol and remifentanil TCI and to the common intraoperative neuromonitoring values as well as to Pupillometry values (in particular Pupil Diameter, Pupil Latency, and Maximum Contraction Velcoity).

NCT Number	NCT03774420
Lead Sponsor	University of Padova
Conditions	Emergence Delirium, Post-Operative Cognitive Dysfunction
Enrollment	200 participants
Start Date	2019-07-03
Primary Completion	2027-11-30 (estimated)
Study Completion	2027-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-04-21