Functional Assessment by Virtual Online Reconstruction. The FAVOR III Europe Trial

Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. QFR is estimated based on two angiographic projections. Studies have shown a good correlation with the present wire-based standard approach Fractional Flow Reserve (FFR) for assessment of intermediate coronary stenosis. The purpose of the FAVOR III Europe Japan study is to investigate if a QFR-based diagnostic strategy will results in non-inferior clinical outcome after 12 months compared to a standard pressure-wire guided strategy in evaluation of patients with chest pain (stable angina pectoris) and intermediate coronary stenosis.

NCT Number	NCT03729739
Lead Sponsor	Aarhus University Hospital Skejby Collaborators: Medis Medical Imaging Systems
Conditions	Coronary Artery Disease
Enrollment	2,001 participants
Start Date	2018-11-06
Primary Completion	2023-07-21 (estimated)
Study Completion	2025-12-31 (estimated)
Updated on ClinicalTrials.gov	2024-07-24