The Biological Rhythm of Human Metabolite

The circadian regulation in mammals have been known for a long time. A special group of clock genes, organized in feedback loops, are responsible for the circadian regulation in both the SCN and peripheral organs. The central clock is mainly entrained by the light-dark cycle, while the peripheral ones in organs such as liver and intestine, are more influenced by the feeding-fasting cycles. The coordination of central and peripheral clocks is thought to be essential in the maintenance of physiological homeostasis.This study aim to investigate the association between biological rhythm and metabolism.

NCT Number	NCT03669809
Lead Sponsor	Shandong Provincial Hospital
Conditions	Rhythm Nodal, Metabolism and Nutrition Disorder, Metabolism Disorder, Lipid
Enrollment	200 participants
Start Date	2011-05-01
Primary Completion	2050-05-01 (estimated)
Study Completion	2050-05-01 (estimated)
Updated on ClinicalTrials.gov	2022-05-11