Post-operative Emesis and Pain Outcomes After Cesarean Delivery

Approximately 20% women who undergo cesarean delivery would suffer from severe post-operative pain, which may further increase their risks from developing postpartum depression. Predictive factors such as pre-operative pain, age and anxiety could significantly contribute to post-operative nausea and vomiting (PONV) and pain in general surgery, however little information is available with regards to cesarean delivery. The investigators would investigate the risk factors of causing post-operative emesis after cesarean delivery, and to reaffirm that there is a positive correlation between pain on local anesthetic injection, presence of mechanical temporal summation (MTS) and post-Cesarean pain scores.

NCT Number	NCT03645239
Lead Sponsor	KK Women's and Children's Hospital
Conditions	Pain, Postoperative, Cesarean Section, Nausea, Postoperative, Vomiting, Postoperative
Enrollment	595 participants
Start Date	2018-05-24
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-07