Clinical Trial

Use of Bone Marrow Derived Stem Cell and G-CSF With Circulatory Assistance in the Treatment of DCM

Study acronym: DCM-Support
Active, Not Recruiting Phase 2
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Summary
DCM Support is recruiting patients with dilated cardiomyopathy and heart failure symptoms. The goal of this clinical trial is to examine whether treatment with a patient's own stem cells can improve their heart function and alleviate heart failure symptoms. * Stem cells will be collected from bone marrow in the patient's hip under local anaesthetic. * The stem cells will be infused into the arteries that supply blood to the heart under local anaesthetic. * A mini heart pump will be used to take the strain off the heart during the procedure. * The follow-up involves a phone call at 1 month and clinic visits at 3 and 12 months
Protocol Amendment History 9 amendments
This ClinicalTrials.gov record has been amended 9 times since 2018-06-19; most recent amendment 2026-04-01.
Status change: Recruiting → Active, Not Recruiting 2026-04-01
Status change: Active, Not Recruiting → Recruiting 2025-07-18
Status change: Recruiting → Active, Not Recruiting 2024-07-31
Status change: Not Yet Recruiting → Recruiting 2019-01-25
Trial Details
NCT Number NCT03572660
Lead Sponsor Barts & The London NHS Trust
Conditions Dilated Cardiomyopathy
Enrollment 20 participants
Start Date 2018-12-24
Primary Completion 2030-03-31 (estimated)
Study Completion 2030-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-06