Clinical Trial

Second and Third Look Laparoscopy in pT4 Colon Cancer Patients for Early Detection of Peritoneal Metastases

Study acronym: COLOPEC-II
Active, Not Recruiting Phase 3
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Record status
This record was last updated February 23, 2024 (before its estimated March 1, 2025 completion). Its status may not reflect the trial's current state.
Summary
The COLOPEC II multicentre randomized trial will investigate the role of second and third look laparoscopy to detect metachronous peritoneal metastases at a clinically occult stage during the follow-up of pT4 colon cancer patients. It is expected that detection of PM at a clinically occult stage will translate into survival benefit, due to higher percentage of patients eligible for curative intent treatment with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
Protocol Amendment History 7 amendments
This ClinicalTrials.gov record has been amended 7 times since 2018-01-26; most recent amendment 2024-02-22.
Status change: Recruiting → Active, Not Recruiting 2024-02-22
Status change: Not Yet Recruiting → Recruiting 2018-02-01
Trial Details
NCT Number NCT03413254
Lead Sponsor Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Conditions Colorectal Cancer, Peritoneal Metastases
Enrollment 389 participants
Start Date 2018-03-01
Primary Completion 2025-03-01 (estimated)
Study Completion 2028-10-01 (estimated)
Updated on ClinicalTrials.gov 2024-02-23