Clinical Trial

Metabolic Profile of Bone in Professional Athletes

Study acronym: SportMarkers

Recruiting

Record status

This record was last updated September 11, 2025 (before its estimated February 4, 2026 completion). Its status may not reflect the trial's current state.

Summary

Physical activity is a key stimulus for bone metabolism through both direct mechanisms (e.g., as a result of the applied load and/or impact) and indirect mechanisms (e.g., the activation of several metabolic pathways and the production of several mediators and effectors that have systemic effects). However, different kinds of physical activity exert different effects on bone and endocrine system. Aim of the study is to investigate the effects of different kinds of physical activity on bone metabolism and on the relationships existing between bone metabolism, energy metabolism, hormone profile, and organ functionality.

Protocol Amendment History 2 amendments

This ClinicalTrials.gov record has been amended 2 times since 2017-12-21; most recent amendment 2025-09-04.

Trial Details

NCT Number	NCT03386981
Lead Sponsor	I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Conditions	Bone Disease, Metabolic, Physical Activity
Enrollment	200 participants
Start Date	2016-02-04
Primary Completion	2026-02-04 (estimated)
Study Completion	2027-02-04 (estimated)
Updated on ClinicalTrials.gov	2025-09-11