Gut Microbiota of Preterm Infants and Full-term Infants at Early Life

The aim of this study is to obtain a longitudinal view of the gut microbial establishment of a cohort of 51 preterm (PT) infants compared to 50 full-term (FT) infants from birth to 90 days of age, and to identify key clinical factors that affect the establishment of neonatal microbiome. The hypothesis of the investigators is that the gut microbiota progression of PT group and FT group is different in diversity and composition. Antibiotics and its usage duration is likely the main factor disturbing the colonization and development of the gut microbiome of PT infants.

NCT Number	NCT03373721
Lead Sponsor	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Conditions	Preterm Infant, Gut Microbiome
Enrollment	102 participants
Start Date	2014-07-20
Primary Completion	2026-11-01 (estimated)
Study Completion	2028-12-20 (estimated)
Updated on ClinicalTrials.gov	2024-04-17