Nurse-Family Partnership Impact Evaluation in South Carolina

This study evaluates the effects of the Nurse Family Partnership (NFP), an established home-visiting program, using a scientifically rigorous individual-level randomized controlled trial. The study will be based in South Carolina, where a Medicaid waiver in combination with a pay-for-success contract will allow expansion of the program to women on Medicaid. The study plans to enroll 4000 low-income, first time mothers and their children into the intervention group, and another 2000 into the control group. The study will evaluate the program's impacts on outcomes using administrative records. This study aims to yield new evidence on the effect of NFP in a modern context, applied to a new population, across a broad range of outcomes, and financed by a novel public-private partnership based on accountability for outcomes.

NCT Number	NCT03360539
Lead Sponsor	Harvard School of Public Health (HSPH) Collaborators: Abdul Latif Jameel Poverty Action Lab, University of Chicago
Conditions	Preterm Birth, Injuries, Maternal Behavior
Enrollment	5,670 participants
Start Date	2016-04-01
Primary Completion	2023-04-01 (estimated)
Study Completion	2046-04-01 (estimated)
Updated on ClinicalTrials.gov	2025-12-12