Berlin-Brandenburg Pregnancy Cohort

This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.

NCT Number	NCT03313024
Lead Sponsor	Charite University, Berlin, Germany
Conditions	Preeclampsia, Pregnancy Complications, Diabetes Mellitus in Pregnancy
Enrollment	1,580 participants
Start Date	2017-09-26
Primary Completion	2027-10 (estimated)
Study Completion	2027-10 (estimated)
Updated on ClinicalTrials.gov	2018-08-14