Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT03255928 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD)

Study acronym: PASVAD
StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary completion date: Dec 31, 2024 to Dec 31, 2026
    • Study completion date: Dec 31, 2025 to Dec 31, 2026
    v7
  2. Primary completion date: Dec 31, 2022 to Dec 31, 2024
    • Study completion date: Dec 31, 2022 to Dec 31, 2025
    v6
  3. Primary and study completion dates: Jan 31, 2022 to Dec 31, 2022
    • Site contact updated
    v5
  4. Primary completion date: Jan 31, 2021 to Jan 31, 2022v4
  5. Primary completion date: Jun 29, 2020 to Jan 31, 2021
    • Study completion date: Jun 29, 2021 to Jan 31, 2022
    v3
  6. Publications: 14 to 16v2
  7. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Consenting patients with end-stage heart failure that are implanted with/candidates for implant of a short-term/durable mechanical circulatory support device (e.g.: percutaneous microaxial pumps (Impella), extracorporeal membrane oxygenator (ECMO), Ventricular Assist Device (VAD) will be enrolled in the study. Aim of the study is to evaluate the patients' haemostatic and coagulation profile, how it interacts with the support device as well as the effect of antithrombotic drugs. From these data, it will be possible to derive the mechanisms triggering post-implant thromboembolic/hemorrhagic complications and to identify potential therapeutic targets.
Trial Details
NCT Number NCT03255928
Lead Sponsor Scientific Institute San Raffaele
Collaborators: Università Vita-Salute San Raffaele
Conditions
(from sponsor)		 Thrombosis, Blood Coagulation Disorder, Platelet Thrombus, Platelet Dysfunction Due to Aspirin, Failure;Ventricular
Related terms Blood Coagulation Disorders, Hemorrhage, Thrombosis
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov