Clinical Trial

Trial Comparing Treatment Strategies in Dupuytren's Contracture

Study acronym: DETECT
Active, Not Recruiting Phase 4
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Record status
This record was last updated April 29, 2026 (before its estimated May 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
Trial is a prospective, randomized, controlled, outcome assessor-blinded, three armed parallel 1:1:1, multicenter trial. The research objective is to determine, which treatment strategy 1) primary percutaneous needle fasciotomy (PNF) followed by surgical limited fasciectomy (LF) in patients who do not respond to PNF, 2) primary collagenase clostridium histolyticym (CCH) followed by LF in patients who do not respond to CCH or 3) LF as the primary (and secondary) treatment modality is the most cost-effective in treating Dupuytren´s contracture. Short- and long-term results will be published.
Protocol Amendment History 11 amendments
This ClinicalTrials.gov record has been amended 11 times since 2017-06-14; most recent amendment 2026-04-28.
Status change: Recruiting → Active, Not Recruiting 2021-02-10
Status change: Not Yet Recruiting → Recruiting 2017-10-26
Trial Details
NCT Number NCT03192020
Lead Sponsor Tampere University
Collaborators: Central Finland Hospital District, Helsinki University Central Hospital, Turku University Hospital, Tampere University Hospital, Kuopio University Hospital, Oulu University Hospital, Medcare Oy, Finnish Institute for Health and Welfare, Orton Orthopaedic Hospital
Conditions Dupuytren Contracture
Enrollment 302 participants
Start Date 2017-09-15
Primary Completion 2026-05-31 (estimated)
Study Completion 2031-05-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-29