Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery

This phase II trial studies the neurological function in patients with multiple brain metastases undergoing stereotactic radiosurgery (SRS) or stereotactic body radiation therapy (SBRT). Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method can kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. Assessment of neurocognitive function may help show that SRS preserves neurological function in patients with multiple brain metastases better than SBRT.

NCT Number	NCT03184038
Lead Sponsor	Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Conditions	Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm
Enrollment	90 participants
Start Date	2017-02-21
Primary Completion	2026-09-30 (estimated)
Study Completion	2026-09-30 (estimated)
Updated on ClinicalTrials.gov	2026-05-22