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Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

StatusRecruiting
PhasePhase 1/2
Started2017-07-31
View on ClinicalTrials.gov ↗
This study has two phases, Phase I and Phase II. The main goal of the Phase I portion of this research study is to see what doses post-transplant inotuzumab ozogamicin can safely be given to subjects without having too many side effects. The Phase II portion of this study is to see what side effects are seen with medication after transplant. Inotuzumab ozogamicin is a combination of an antibody and chemotherapy which has been shown to have significant activity against relapsed/refractory acute lymphocytic leukemia (ALL). Inotuzumab ozogamicin is considered experimental in this study.

Amendment history 1 change detected by DataLookout

2026-09-11
critical
Primary completion pushed: 2025-11 → 2026-11
Trial Details
NCT Number NCT03104491
Lead Sponsor Leland Metheny
Conditions Acute Lymphocytic Leukemia
Enrollment 44 participants
Start Date 2017-07-31
Primary Completion 2026-11 (estimated)
Study Completion 2027-05 (estimated)
Updated on ClinicalTrials.gov 2026-09-10