Clinical Trial

Microbiota and the Lung Cancer

Study acronym: MICA
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The subject is to study the lung microbiota and the one of upper airways (UAs) (much less studied than the intestinal microbiota) in 40 patients having lung cancer. 20 patients undergo only surgical treatment, while other half receives also chemotherapy. The idea is to explore changes in microbiota of the lung, upper UAs and intestine, and potentially find associations between them. These results will serve us as a base for the future study, focused on manipulation of the microbiota by prebiotics, probiotics or symbiotics and its effect on anti-cancer treatment tolerance and effectiveness.
Protocol Amendment History 9 amendments
This ClinicalTrials.gov record has been amended 9 times since 2017-02-27; most recent amendment 2026-03-18.
Status change: Recruiting → Active, Not Recruiting 2026-03-18
Status change: Not Yet Recruiting → Recruiting 2017-07-18
Trial Details
NCT Number NCT03068663
Lead Sponsor Centre Jean Perrin
Collaborators: Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Université d'Auvergne, GREENTECH SA
Conditions Non Small Cell Lung Cancer
Enrollment 40 participants
Start Date 2017-05-23
Primary Completion 2029-10-30 (estimated)
Study Completion 2029-10-30 (estimated)
Updated on ClinicalTrials.gov 2026-03-20