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NCT02870738 · ClinicalTrials.gov record · last posted 2026-07-09

Bladder Directed vs. Pelvic Floor Therapy in IC/BPS

StatusActive, Not Recruiting
PhasePhase 2
Started2017-04-21
View on ClinicalTrials.gov ↗
from the ClinicalTrials.gov record
Women with interstitial cystitis/bladder pain syndrome (IC/BPS) have debilitating urinary frequency and urgency, and chronic pelvic or bladder pain perceived to be related to the bladder. Although many clinicians think that IC/BPS symptoms result from a bladder problem, tight pelvic floor muscles can cause similar symptoms and might be responsible for ICBPS symptoms instead of the bladder. Inadequate assessment of the problem leads to delays in treatment and often years of suffering. This clinical trial will test a bladder directed therapy (bladder instillations) compared to a course of pelvic floor physical therapy (PFPT) to assess the role of the pelvic floor as a major contributor to pelvic pain and voiding dysfunction in adult women with non-ulcerative IC/BPS. Early assessment of the pelvic floor muscles in patients with IC/BPS symptoms may prevent common delays in proper diagnosis and allow for early, more effective treatment.

Protocol amendment history 1 change detected by DataLookout

2026-07-10
minor
Completion pushed: 2026-08 → 2027-08
Trial Details
NCT Number NCT02870738
Lead Sponsor Corewell Health East
Collaborators: Baylor College of Medicine
Conditions Cystitis, Interstitial, Painful Bladder Syndrome
Enrollment 128 participants
Start Date 2017-04-21
Primary Completion 2026-02-03 (estimated)
Study Completion 2027-08 (estimated)
Updated on ClinicalTrials.gov 2026-07-09