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Intravitreal Adalimumab Versus Subcutaneous Adalimumab in Non-infectious Uveitis

Study acronym: IVAS
StatusRecruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated February 26, 2025 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.

Record History

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  1. Re-verified, no change to tracked fieldsv4
  2. Primary completion date: Dec 2018 to Dec 2025
    • Study completion date: Jun 2019 to Feb 2026
    v3
  3. Secondary endpoints revised (4)v2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The objective of this study is to compare and evaluate the efficacy of subcutaneous (40mg) adalimumab biweekly injections to intravitreal adalimumab (1.5 mg/ 0.03 mL) administration, given at zero, 2 weeks then every four weeks, in subjects with active non-infectious intermediate-, posterior-, or pan-uveitis.
Trial Details
NCT Number NCT02706704
Lead Sponsor American University of Beirut Medical Center
Conditions
(from sponsor)		 Uveitis, Non-Infectious Uveitis
Related terms Uveitis
Enrollment 32 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov