Physical Exercise Augmented CBT for GAD

Generalised anxiety disorder (GAD) is a severe and debilitating anxiety disorder that is highly prevalent among older adults. Anxiety and GAD is a well-documented risk factor for the development of other severe conditions such as depression and dementia, and effective treatments are called for. However, recommended treatment for GAD has consistently been found to yield blunted response rates for older adults compared to younger patients. The purpose of this study is to evaluate the effects of exercise-augmented cognitive behaviour therapy for older adults with GAD. Exercise augmented CBT is expected to yield better results than standard CBT in terms of greater reduction of symptoms and increased rates of remission. The investigators will also investigate the effects of treatment on biological, physiological and neuropsychological measures.

NCT Number	NCT02690441
Lead Sponsor	Solli Distriktspsykiatriske Senter Collaborators: University of Bergen, Norwegian University of Science and Technology, University of Oslo, University of California, Berkeley, William Paterson University of New Jersey, Ohio State University
Conditions	Generalized Anxiety Disorder
Enrollment	53 participants
Start Date	2016-03
Primary Completion	2023-10 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2026-04-28