Latent Structure of Multi-level Assessments and Predictors of Outcomes for Women in Recovery

In this study the investigators will seek to improve their understanding of how positive and negative valence systems, cognition, and arousal/interoception are inter-related in disorders of trauma, mood, substance use, and eating behavior for women involved in a court diversion program in Tulsa, Oklahoma (Women in Recovery). The investigators will recruit 100 individuals and use a wide range of assessment tools, neuroimaging measures, blood and microbiome collections and behavioral tasks to complete the baseline and follow-up study visits. Upon completion, the investigators aim to have robust and reliable dimensional measures that quantify these systems and a set of assessments that should be recommended as a clinical tool to enhance outcome prediction for the clinician and assist in determining who will likely benefit from the diversion program, and to inform future revision or augmentation of the program to increase treatment effectiveness.

NCT Number	NCT02601495
Lead Sponsor	Laureate Institute for Brain Research, Inc. Collaborators: University of Oklahoma, Rutgers University, University of California, San Diego
Conditions	Depression, Anxiety, Eating Disorders, Drug Use Disorders, Stress Disorders, Post-Traumatic
Enrollment	100 participants
Start Date	2015-11
Primary Completion	2020-01 (estimated)
Study Completion	2028-11 (estimated)
Updated on ClinicalTrials.gov	2023-08-14