Clinical Trial

The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in Brazil

Active, Not Recruiting Phase 2
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Record status
This record was last updated January 16, 2024 (before its estimated August 2025 completion). Its status may not reflect the trial's current state.
Summary
Mucocutaneous leishmaniasis is endemic in the central region of Brazil and other countries worldwide. The standard treatment with meglumine antimoniate has a high rate of important adverse effects. This interventional study consists in a randomized clinical trial to access efficacy and safety of the association of miltefosine and pentoxifylline compared to meglumine antimoniate and pentoxifyline.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2015-08-20; most recent amendment 2024-01-11.
Status change: Recruiting → Active, Not Recruiting 2022-05-23
Trial Details
NCT Number NCT02530697
Lead Sponsor University of Brasilia
Conditions Leishmaniasis
Enrollment 160 participants
Start Date 2015-08
Primary Completion 2025-08 (estimated)
Study Completion 2026-08 (estimated)
Updated on ClinicalTrials.gov 2024-01-16