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Pediatric Arm of DZL All Age Asthma Cohort

Study acronym: ALLIANCE
StatusRecruiting
PhaseNot specified
Started
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Record History

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  1. Notable Primary and study completion dates: Dec 2023 to Dec 2027
    • Site contacts updated at 4 of 5 sites
    v9
  2. Notable Primary and study completion dates: Dec 2020 to Dec 2023v8
  3. Minor Re-verified, no change to tracked fieldsv7
  4. Minor Study description shortened, about 9 words
    • Site contacts updated at 1 of 5 sites
    v6
  5. Notable Enrollment target: 500 to 1500
    • Study sites: 4 to 5
    • Study description shortened, about 101 words
    v5
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  1. Minor Study title expanded, about 4 wordsv4
  2. Minor Re-verified, no change to tracked fieldsv3
  3. Notable Primary and study completion dates: Dec 2015 to Dec 2020
    • Enrollment target: 360 to 500
    v2
  1. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
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Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood. Therefore, deciphering underlying determinants for different childhood and adult asthma phenotypes is urgently needed to develop personalized treatment approaches targeting distinct underlying mechanisms. Thereby, secondary prevention early in the disease process can also be achieved. The decoding of such mechanisms and their translation to the individual patient is the aim of the Disease Area Asthma Allergy of the 'German Centre for Lung Research' (DZL).
Trial Details
NCT Number NCT02496468
Lead Sponsor LMU Klinikum
Collaborators: German Federal Ministry of Education and Research, German Center for Lung Research, Comprehensive Pulmonary Center Munich, Airway Research Center North, Biomedical Research in Endstage and Obstructive Lung Disease Hannover, Translational Lung Research Center Heidelberg, Universities of Giessen and Marburg Lung Center
Conditions
(from sponsor)
Asthma, Wheeze, Hypersensitivity, Endophenotype
Related terms Asthma, Hypersensitivity, Respiratory Sounds
Enrollment 1,500 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov