Pediatric Arm of DZL All Age Asthma Cohort

Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood. Therefore, deciphering underlying determinants for different childhood and adult asthma phenotypes is urgently needed to develop personalized treatment approaches targeting distinct underlying mechanisms. Thereby, secondary prevention early in the disease process can also be achieved. The decoding of such mechanisms and their translation to the individual patient is the aim of the Disease Area Asthma Allergy of the 'German Centre for Lung Research' (DZL).

NCT Number	NCT02496468
Lead Sponsor	LMU Klinikum Collaborators: German Federal Ministry of Education and Research, German Center for Lung Research, Comprehensive Pulmonary Center Munich, Airway Research Center North, Biomedical Research in Endstage and Obstructive Lung Disease Hannover, Translational Lung Research Center Heidelberg, Universities of Giessen and Marburg Lung Center
Conditions	Asthma, Wheeze, Hypersensitivity, Endophenotype
Enrollment	1,500 participants
Start Date	2013-01
Primary Completion	2027-12 (estimated)
Study Completion	2027-12 (estimated)
Updated on ClinicalTrials.gov	2024-08-28