Clinical Trial

Immune Function in Acute Kidney Injury

Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The immune response to kidney damage during acute kidney injury (AKI) is an important contributor to the prolonged lack of renal function and progression of kidney injury. Most data related to intrarenal and interorgan pathways in AKI stem from animal research with sometimes conflicting results. Accurate evaluation of these processes in humans and identification of early diagnostic tools are critical for the development of strategies to prevent and attenuate AKI-related morbidity and mortality in patients. The aim of this study is to evaluate immune function and miRNA expression in hospitalised patients with and without AKI.
Protocol Amendment History 7 amendments
This ClinicalTrials.gov record has been amended 7 times since 2015-06-11; most recent amendment 2024-01-22.
Status change: Recruiting → Active, Not Recruiting 2019-10-21
Trial Details
NCT Number NCT02470507
Lead Sponsor Guy's and St Thomas' NHS Foundation Trust
Collaborators: King's College London
Conditions Acute Kidney Failure
Enrollment 120 participants
Start Date 2013-06
Primary Completion 2022-08-01 (estimated)
Study Completion 2026-12-01 (estimated)
Updated on ClinicalTrials.gov 2024-01-23