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NCT02447874 · ClinicalTrials.gov record · last posted 2026-07-29

Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease

Name: Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease — clinical trial record (NCT02447874)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: R34 pK/PD

StatusRecruiting

PhasePhase 1/2

SponsorEmory University

Started2015-05

View on ClinicalTrials.gov ↗

from the ClinicalTrials.gov record

The purpose of this study is to determine whether giving extra arginine to patients with sickle cell disease seeking treatment for vaso-occlusive painful events (VOE) will decrease pain scores, decrease need for pain medications or decrease length of hospital stay or emergency department visit.

Protocol amendment history 2 changes detected by DataLookout

2026-07-30

Primary completion pushed: 2026-07 → 2028-01

2026-07-30

Completion pushed: 2026-07 → 2028-01

Trial Details

NCT Number	NCT02447874
Lead Sponsor	Emory University Collaborators: Children's Healthcare of Atlanta, National Center for Complementary and Integrative Health (NCCIH)
Conditions	Sickle Cell Disease
Enrollment	21 participants
Start Date	2015-05
Primary Completion	2028-01 (estimated)
Study Completion	2028-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-29