Clinical Trial

Assessing the Impact of Contraceptives on Bone Health Using 41Ca

Active, Not Recruiting Phase 4
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Summary
This preclinical randomized crossover study will examine the effects of oral versus non-oral contraceptive therapy on bone turnover in young exercising women. In an effort to expose the route-dependent effects of oral versus non-oral contraceptive therapy on bone turnover, the investigators will examine 1) the effects of ethinyl estradiol on bone calcium balance using the 41Ca technology and 2) the underlying physiological mechanisms associated with the effects of oral versus non-oral contraceptive therapy on net bone calcium balance.
Protocol Amendment History 11 amendments
This ClinicalTrials.gov record has been amended 11 times since 2015-02-13; most recent amendment 2026-07-02.
Status change: Recruiting → Active, Not Recruiting 2017-05-03
Trial Details
NCT Number NCT02367846
Lead Sponsor Penn State University
Collaborators: Purdue University
Conditions Other Disorders of Bone Development and Growth
Enrollment 6 participants
Start Date 2015-01
Primary Completion 2028-12 (estimated)
Study Completion 2028-12 (estimated)
Updated on ClinicalTrials.gov 2026-07-06