Clinical Trial

Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury

Recruiting
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Summary
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with chronic spinal cord injury (SCI). The goal of the study is to understand the mechanisms by which intermittent hypoxia enhances motor function and spinal plasticity (ability of the nervous system to strengthen neural pathways based on new experiences) following SCI.
Protocol Amendment History 13 amendments
This ClinicalTrials.gov record has been amended 13 times since 2014-12-23; most recent amendment 2026-03-18.
Trial Details
NCT Number NCT02323945
Lead Sponsor Spaulding Rehabilitation Hospital
Collaborators: Foundation Wings For Life, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions Spinal Cord Injuries
Enrollment 44 participants
Start Date 2014-10
Primary Completion 2027-08 (estimated)
Study Completion 2027-11 (estimated)
Updated on ClinicalTrials.gov 2026-03-20