Clinical Trial

Research on Infarction With Open Arteries Using OCT and CMR

Study acronym: RIO
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The purpose of this study is to determine the prevalence of plaque disruption and to assess the composition of disrupted plaques in patients with myocardial infarction (MI) and non-obstructive coronary artery disease (CAD) using optical coherence tomography (OCT). Additionally, cardiac magnetic resonance imaging (CMR) will be used to detect myocardial abnormalities, which will be correlated to OCT findings to gain insight into the mechanisms of MI in patients with non-obstructive coronary artery disease (i.e. "open arteries").
Protocol Amendment History 2 changes
notable Primary completion pushed: 2025-10-31 -> 2027-12-31 2026-08-01
minor Completion pushed: 2025-10-31 -> 2027-12-31 2026-08-01
Trial Details
NCT Number NCT02270359
Lead Sponsor NYU Langone Health
Conditions Myocardial Infarction
Enrollment 15 participants
Start Date 2014-04
Primary Completion 2027-12-31 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-31