Clinical Trial

Assessment of Antibodies and Inflammatory Markers in Postural Tachycardia Syndrome

Active, Not Recruiting
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Summary
In this pilot study, the investigators will test the hypothesis that patients with postural tachycardia syndrome will have an elevated percentage of functional antibodies to adrenergic receptors compared with control subjects without POTS. The investigators further hypothesize that the percentage of POTS patients with antibodies will be higher in those patients with a viral infection at the onset of their illness than in those patients with other or undefined illness onsets.
Protocol Amendment History 12 amendments
This ClinicalTrials.gov record has been amended 12 times since 2014-07-18; most recent amendment 2025-10-08.
Status change: Recruiting → Active, Not Recruiting 2016-08-15
Trial Details
NCT Number NCT02196376
Lead Sponsor Vanderbilt University
Conditions Postural Orthostatic Tachycardia Syndrome
Enrollment 212 participants
Start Date 2014-07
Primary Completion 2029-07 (estimated)
Study Completion 2029-07 (estimated)
Updated on ClinicalTrials.gov 2025-10-10