The North Sea Race Endurance Exercise Study

Competitions such as marathon running and endurance cycling events are increasingly popular and represent an important motivation for sustaining training among leisure-time athletes. However, there is a concern that prolonged, high-intensity exercise may increase the risk of cardiovascular (CV) events. Following prolonged high-intensity exercise there is an increase in levels of circulating markers of myocardial damage such as Troponin I (TnI). The precise cause and clinical significance of this TnI increase is unknown. * The primary objective of this study was to determine the relationship between high-sensitive cardiac troponin I (hs-cTnI) levels and coronary artery disease and cardiovascular outcomes in 1000 presumably healthy leisure sport athletes that participated in a 91 km long, high intensity endurance cycling competition. * The secondary objective was to assess the relationship between other CV risk factors, fitness level and outcomes following high intensity endurance cycling competition in the same population.

NCT Number	NCT02166216
Lead Sponsor	Helse Stavanger HF Collaborators: Nordsjørittet, Abbott
Conditions	Healthy
Enrollment	1,200 participants
Start Date	2013-06
Primary Completion	2034-06 (estimated)
Study Completion	2034-06 (estimated)
Updated on ClinicalTrials.gov	2017-10-19