Clinical Trial

Endothelin Receptor Function and Acute Stress

Study acronym: End-Stress
Active, Not Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated January 28, 2025 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.
Summary
Our bodies respond differently to stress. Animal studies by the investigators have found that endothelin-1 plays a role in regulating blood pressure in response to stress. This study is an extension of the investigators previous animal work to evaluate the role of endothelin-1 during stress in humans.
Protocol Amendment History 14 amendments
This ClinicalTrials.gov record has been amended 14 times since 2014-04-15; most recent amendment 2025-01-27.
Status change: Recruiting → Active, Not Recruiting 2020-07-09
Status change: Not Yet Recruiting → Recruiting 2015-07-17
Trial Details
NCT Number NCT02116335
Lead Sponsor Augusta University
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
Conditions Hypertension
Enrollment 320 participants
Start Date 2015-06
Primary Completion 2025-12 (estimated)
Study Completion 2026-01 (estimated)
Updated on ClinicalTrials.gov 2025-01-28