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Endothelin Receptor Function and Acute Stress

Study acronym: End-Stress
StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated January 28, 2025 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.

Record History

See every version on ClinicalTrials.gov ↗

  1. Re-verified, no change to tracked fieldsv15
  2. Primary completion date: Dec 2023 to Dec 2025
    • Study completion date: Jan 2024 to Jan 2026
    v14
  3. Primary completion date: Dec 2021 to Dec 2023
    • Study completion date: Jul 2022 to Jan 2024
    v13
  4. Primary completion date: Sep 2021 to Dec 2021
    • Study completion date: Sep 2021 to Jul 2022
    • Secondary endpoints: 4 to 5
    v12
  5. Primary and study completion dates: Sep 2020 to Sep 2021v11
Show 9 earlier versionsHide 9 earlier versions
  1. Trial status: Recruiting to Active, Not Recruiting
    • Primary and study completion dates: Apr 2020 to Sep 2020
    • Site details revised
    v10
  2. Primary completion date: Apr 2019 to Apr 2020v9
  3. 4 versions Re-verified since Feb 9, 2016, no change to tracked fieldsv5-v8
  4. Study description expanded, about 1 wordv4
  5. Trial status: Not Yet Recruiting to Recruiting
    • Start date: Jan 2015 to Jun 2015
    • Site details revised
    v3
  6. Start date: May 2014 to Jan 2015v2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Augusta University
25 trials monitored
See 1 trial at risk
Hypertension
1,925 trials monitored
See 99 trials at risk
Our bodies respond differently to stress. Animal studies by the investigators have found that endothelin-1 plays a role in regulating blood pressure in response to stress. This study is an extension of the investigators previous animal work to evaluate the role of endothelin-1 during stress in humans.
Trial Details
NCT Number NCT02116335
Lead Sponsor Augusta University
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
Conditions
(from sponsor)		 Hypertension
Related terms Hypertension, Inflammation
Enrollment 320 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov