The purpose of this study is to compare 3 cycles of neoadjuvant (preoperative) chemotherapy + operation with the standard treatment of locally advanced colon cancer, which is operation + 8 cycles of (adjuvant) chemotherapy.
Patients receiving neoadjuvant chemotherapy may not need adjuvant chemotherapy after the operation and, if this is the case, they will be spared of 5 cycles of chemotherapy.
Protocol Amendment History
17 amendments
This ClinicalTrials.gov record has been amended 17 times since 2013-08-06; most recent amendment 2026-03-06.
Status change: Recruiting → Active, Not Recruiting2021-09-27
Status change: Not Yet Recruiting → Recruiting2013-09-19