Clinical Trial

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

Recruiting Phase 1/2
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Summary
This Phase I/II trial studies the ability to stop brain metastases from coming back after treatment with radiosurgery followed by surgical resection. It will also evaluate the side effects of these combined treatments and help determine the best radiosurgery dose. Radiosurgery focuses the x-rays directly to the tumor and cause less damage to the normal tissue in the brain.
Protocol Amendment History 29 amendments
This ClinicalTrials.gov record has been amended 29 times since 2013-06-28; most recent amendment 2026-06-25.
Status change: Not Yet Recruiting → Recruiting 2013-07-11
Trial Details
NCT Number NCT01891318
Lead Sponsor Case Comprehensive Cancer Center
Conditions Tumors Metastatic to Brain
Enrollment 36 participants
Start Date 2013-07-03
Primary Completion 2026-09 (estimated)
Study Completion 2026-09 (estimated)
Updated on ClinicalTrials.gov 2026-08-06