Vitamin D and Physical Activity on Bone Health

This research will examine the effectiveness of vitamin D or placebo (the placebo is a tablet that looks like Vitamin D study drug, but has no Vitamin D study drug in it), with and without physical activity (walking and progressive resistance exercise), in treating bone loss in women who have undergone treatment for breast cancer. The investigators would also like to find out if the physical activity program improves cardiovascular fitness, energy expenditure, muscular strength, muscle mass, and balance. One hundred five (105) subjects are expected to take part in this study. The investigators don't know if bone loss in breast cancer survivors should be treated differently than bone loss in other women.

NCT Number	NCT01419730
Lead Sponsor	University of Rochester
Conditions	Bone Metabolism Biomarkers, Bone Mineral Density, Physical Fitness
Enrollment	191 participants
Start Date	2011-08
Primary Completion	2024-12-30 (estimated)
Study Completion	2026-12-30 (estimated)
Updated on ClinicalTrials.gov	2026-08-05