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Study of the Effect of Innate on the Inflammatory Response to Endotoxin

StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Record History

The 50 most recent of 305 record versions are accounted for below. See every version on ClinicalTrials.gov ↗

  1. Re-verified, no change to tracked fields
  2. Eligibility criteria expanded, about 4 words
  3. 8 versions Re-verified since Apr 7, 2026, no change to tracked fieldsv296-v303
  4. Study Status, Eligibilityv295
  5. 33 versions Re-verified since Jul 25, 2023, no change to tracked fieldsv262-v294
Show 6 earlier versionsHide 6 earlier versions
  1. Study Status, Eligibility, Contacts/Locationsv261
  2. 5 versions Re-verified since Dec 7, 2022, no change to tracked fieldsv256-v260
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Background: \- Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation. Researchers are interested in studying how the body responds to certain environmental factors, and whether the body s response can contribute to chronic illnesses or diseases such as asthma and certain types of cancers. Objectives: \- To examine how specific genes and proteins in blood cells respond to environmental exposures. Eligibility: \- Healthy volunteers between 18 and 45 years of age. Design: * The study will involve one visit of 45 to 60 minutes. * Participants will be screened with a brief physical examination and finger stick to determine if they are eligible to donate blood for the study, and will complete a questionnaire about any medications or other drugs (e.g., cigarettes) they may be taking. * Participants will provide a blood sample for research purposes.
Trial Details
NCT Number NCT01143480
Lead Sponsor National Institute of Environmental Health Sciences (NIEHS)
Conditions
(from sponsor)		 Asthma, Atherosclerosis, Metabolic Syndrome, Insulin Resistance, Cancer
Related terms Asthma, Atherosclerosis, Insulin Resistance, Metabolic Syndrome, Neoplasms
Enrollment 725 participants
Start Date
Updated on ClinicalTrials.gov