Clinical Trial

Multicenter ACL Revision Study (MARS)

Study acronym: MARS
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The purpose of this study is to determine the effects of modifiable risk factors on patient-reported quality of life, physical activity levels, and risk of early osteoarthritis following revision anterior cruciate ligament (ACL) reconstruction. The investigators hypothesize that modifiable variables exist at the time of revision ACL reconstruction (e.g., cause of failure, current graft source and type, surgical exposure, and femoral and tibial tunnel position) which will be predictors of patient-reported outcomes.
Protocol Amendment History 15 amendments
This ClinicalTrials.gov record has been amended 15 times since 2008-02-19; most recent amendment 2025-06-12.
Status change: Enrolling by Invitation → Active, Not Recruiting 2014-10-30
Trial Details
NCT Number NCT00625885
Lead Sponsor Vanderbilt University
Collaborators: Vanderbilt University Medical Center, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Conditions Rupture of Anterior Cruciate Ligament
Enrollment 1,234 participants
Start Date 2006-03-26
Primary Completion 2029-06-01 (estimated)
Study Completion 2029-08-31 (estimated)
Updated on ClinicalTrials.gov 2025-06-17