Clinical Trial

Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma

Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
Adrenocortical carcinoma (ACC) is a rare and heterogeneous malignancy with poor prognosis. Surgical resection of the tumor is the treatment of choice. However, even after complete resection more than 80 % of patients will experience recurrence of disease. Therefore, new treatment options are urgently needed. This pre-clinical study try to lay the foundations for a successful immunotherapy in patients with ACC.
Protocol Amendment History 17 amendments
This ClinicalTrials.gov record has been amended 17 times since 2007-04-04; most recent amendment 2026-05-01.
Status change: Recruiting → Active, Not Recruiting 2025-08-24
Status change: Active, Not Recruiting → Recruiting 2021-06-01
Status change: Recruiting → Active, Not Recruiting 2010-07-07
Trial Details
NCT Number NCT00457587
Lead Sponsor University of Wuerzburg
Collaborators: Deutsche Krebshilfe e.V., Bonn (Germany)
Conditions Adrenocortical Carcinoma, Cushing's Syndrome
Enrollment 150 participants
Start Date 2005-09
Primary Completion 2029-12 (estimated)
Study Completion 2030-12 (estimated)
Updated on ClinicalTrials.gov 2026-05-07