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Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma

StatusActive, Not Recruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Record History

  1. Primary completion date: Dec 2027 to Dec 2029
    • Study completion date: Dec 2028 to Dec 2030
    v18
  2. Primary completion date: Dec 2025 to Dec 2027v17 Show 4 more changesShow less
    • Trial status: Recruiting to Active, Not Recruiting
    • Enrollment target: estimated 200 to confirmed 150
    • Study completion date: Dec 2026 to Dec 2028
    • Site details revised
  3. Re-verified, no change to tracked fieldsv16
  4. Primary completion date: Dec 2023 to Dec 2025
    • Study completion date: Dec 2024 to Dec 2026
    v15
  5. Primary completion date: Dec 2025 to Dec 2023
    • Study completion date: Dec 2026 to Dec 2024
    v14
Show 12 earlier versionsHide 12 earlier versions
  1. Trial status: Active, Not Recruiting to Recruitingv13 Show 4 more changesShow less
    • Enrollment target: 70 to 200
    • Primary completion date: Dec 2011 to Dec 2025
    • Study completion date: Dec 2018 to Dec 2026
    • Site details revised
  2. Study completion date: Dec 2017 to Dec 2018v12
  3. Study completion date: Dec 2016 to Dec 2017v11
  4. Re-verified, no change to tracked fieldsv10
  5. Study completion date: Dec 2013 to Dec 2016v9
  6. Primary completion date changed from estimate of Dec 2010 to Dec 2011
    • Study completion date: Dec 2011 to Dec 2013
    v8
  7. Trial status: Recruiting to Active, Not Recruiting
    • Primary completion date: Jun 2010 to Dec 2010
    • Study completion date: Dec 2010 to Dec 2011
    • Site details revised
    v7
  8. Re-verified, no change to tracked fieldsv6
  9. Phase: Early Phase 1 to Not specified
    • Primary completion date: Jun 2010
    • Study completion date: Dec 2009 to Dec 2010
    • Site contact updated
    v5
  10. 3 versions Re-verified since Apr 9, 2007, no change to tracked fieldsv2-v4
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Adrenocortical carcinoma (ACC) is a rare and heterogeneous malignancy with poor prognosis. Surgical resection of the tumor is the treatment of choice. However, even after complete resection more than 80 % of patients will experience recurrence of disease. Therefore, new treatment options are urgently needed. This pre-clinical study try to lay the foundations for a successful immunotherapy in patients with ACC.
Trial Details
NCT Number NCT00457587
Lead Sponsor University of Wuerzburg
Collaborators: Deutsche Krebshilfe e.V., Bonn (Germany)
Conditions
(from sponsor)		 Adrenocortical Carcinoma, Cushing's Syndrome
Related terms Adrenocortical Carcinoma, Cushing Syndrome
Enrollment 150 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov