Clinical Trial

Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Previously Untreated Stage I or Stage II Hodgkin's Lymphoma

Active, Not Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill cancer cells. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving radiation therapy together with combination chemotherapy may kill more cancer cells. It is not yet known whether radiation therapy is more effective with or without combination chemotherapy in treating patients with Hodgkin's lymphoma. PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works with or without combination chemotherapy in treating patients with previously untreated stage I or stage II Hodgkin's lymphoma.
Protocol Amendment History 21 amendments
This ClinicalTrials.gov record has been amended 21 times since 2006-09-20; most recent amendment 2025-08-04.
Trial Details
NCT Number NCT00379041
Lead Sponsor European Organisation for Research and Treatment of Cancer - EORTC
Conditions Lymphoma
Enrollment 1,158 participants
Start Date 1993-09-01
Primary Completion 1998-10-01 (estimated)
Updated on ClinicalTrials.gov 2025-08-05