A 1-Year Study in Multiple Clinics Testing Rebamipide Eye Drops for Dry Eye Compared With a Placebo

Amendment history

1. Jun 10, 2026

   Minor

   Enrollment target: estimated 740 to confirmed 755

   Primary completion date: Feb 1, 2007; Completion date: Feb 2007 to Feb 1, 2007; Start date: May 2004 to May 1, 2004; and 3 more

   Show all 7 changes in this update

   • Minor Enrollment target: estimated 740 to confirmed 755
   • Minor Primary completion date: Feb 1, 2007
   • Minor Completion date: Feb 2007 to Feb 1, 2007
   • Minor Start date: May 2004 to May 1, 2004
   • Minor Interventions: Rebamipide (Drug) to Placebo (Drug), Rebamipide 1% (Drug), Rebamipide 2% (Drug)
   • Minor Site details revised at 1 of 63 sites
   • Minor Study title expanded, about 8 words
     Show what changed

     A 1-Year Study ofin Multiple Clinics Testing Rebamipide Eye Drops to Treatfor Dry Eye Compared With a Placebo

   Study Identification, Study Status, Sponsor/Collaborators, Study Design, Arms and Interventions, Contacts/Locations, References · v5

2. Jan 4, 2008

   Minor

   Trial status: Active, Not Recruiting to Completed

   Completion date: Jan 2007 to Feb 2007; Secondary endpoints: details revised at 1 of 1 entry; Study arms: 0 to 3

   Study Status, Sponsor/Collaborators, Study Design, Arms and Interventions, Outcome Measures, Contacts/Locations, References · v4

3. Oct 31, 2006

   Minor

   Trial status: Recruiting to Active, Not Recruiting

   Site details revised at 63 of 63 sites

   Study Status, Contacts/Locations · v3

4. Sep 26, 2005

   Minor

   Study sites: 1 to 63

   Study Status, Contacts/Locations · v2

5. Sep 12, 2005

   Minor

   Study First Submitted

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.