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Cytapheresis of Volunteer Donors

StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Amendment history

The 50 most recent of 274 record versions are accounted for below. See every version on ClinicalTrials.gov ↗

  1. Minor

    Re-verified, no change to tracked fields

  2. Minor

    Re-verified, no change to tracked fields

  3. Minor

    Re-verified, no change to tracked fields

  4. Minor

    Eligibility criteria expanded, about 39 words

    Show what changed: Eligibility criteria
    * INCLUSION CRITERIA: * Normal healthy males and females, age 18 years and older * Adequate venous access in bilateral upper extremities to accommodate at least a #18 gauge dialysis needle. * Willingness and ability to come to the NIA Apheresis Unit at [...] procedure approximately every 56 days. EXCLUSION CRITERIA: * Unable to verify identification of volunteer by state issued [...] 1099 form, therefore, positive identification is required. * Unable to provide informed consent * Weight less than 110 pounds as mandated by AABB guidelines. * Chronic Immunosuppressive medications such as Steroids, Cell [...] s pro [...]

  5. Minor

    46 amendments

    46 re-verifications since 2025-08-22, no change to tracked fields

    v225-v270

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Background: \- National Institute on Aging researchers are looking at studies that require large numbers of white blood cells for lab use. Standard blood samples do not provide enough white blood cells for these studies. Researchers want to use cytapheresis to collect white blood cells from volunteer donors. This procedure can collect larger amounts of white blood cells and reduce the amount of fluid and other cells that are lost. Objectives: \- To use cytapheresis to collect white blood cells for study. Eligibility: \- Healthy blood donors at least 18 years of age. Design: * Participants will be screened according to the usual blood donation procedures. * Participants will provide white blood cells through cytapheresis. The blood cells will be collected in a machine that separates the white blood cells from the rest of the blood. The rest of the blood will be returned to the donor. * Participants may have this type of donation every 56 days (six times per year). They will be asked to become a repeat donor. A donation schedule may be set up. * Once a year, participants will have blood tests to continue to be eligible as a donor.
Trial Details
NCT Number NCT00104325
Lead Sponsor National Institute on Aging (NIA)
Conditions Healthy Volunteers
Enrollment 10,000 participants
Start Date
Updated on ClinicalTrials.gov