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Studies of the Natural History of Rheumatic Diseases

StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Amendment history

The 50 most recent of 394 record versions are accounted for below. See every version on ClinicalTrials.gov ↗

  1. Notable

    Primary endpoints: details revised at 1 of 1 entry

    Eligibility criteria expanded, about 1 word; Publications: details revised at 3 of 3 entries

    Show what changed: Eligibility criteria
    * INCLUSION CRITERIA: Known or suspected rheumatic disease Age [...]

  2. Minor

    37 amendments

    37 re-verifications since 2025-07-10, no change to tracked fields

    v357-v393

  3. Minor

    Study description revised

    Show what changed: Study description
    [...] physician. All patients referred to this study must have a primaryhealth care provider provide a referral. The establishment of this [...]

    Study Status, Study Descriptionv356

  4. Minor

    6 amendments

    6 re-verifications since 2025-05-31, no change to tracked fields

    v350-v355

  5. Minor

    Study title revised

    Show what changed: Study title
    Studies of the Natural History of Rheumatic DiseaseDiseases

    Study Identification, Study Statusv349

  6. Minor

    4 amendments

    4 re-verifications since 2025-04-23, no change to tracked fields

    v345-v348

  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study will explore the causes of rheumatic diseases and why many of them affect certain minority communities more severely. Rheumatic diseases may cause joint pain, stiffness or swelling. Some can involve bones, muscles, tendons or ligaments. Some cause abnormalities of the immune system-the body s defense against disease. Some rheumatic diseases are painful or deforming and some can be life threatening. Information obtained from this study will be used to learn about the disparities in rheumatic disease in the minority community and to design further, more targeted, research studies to address this issue. Patients with known or suspected rheumatic disease 18 years of age or older may be eligible for this study. Candidates will undergo a medical history and physical examination to confirm the diagnosis of rheumatic disease and determine what is needed for evaluation and treatment. Participants will receive standard medical care for rheumatic disease and arthritis. No experimental treatments, medications or procedures will be included in this study. Procedures may include routine blood tests for blood chemistries, cell counts, and antibodies commonly found in patients with rheumatic disease; a urine test for proteins and cells; and X-rays and other imaging tests to check for abnormalities in the lungs or other organs. All medical information will be kept confidential. Patients who are found to be eligible for other current NIH research studies will be offered an opportunity to participate in these studies.
Trial Details
NCT Number NCT00024479
Lead Sponsor National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Conditions Rheumatic Diseases, Arthritis
Enrollment 7,500 participants
Start Date
Updated on ClinicalTrials.gov