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Phenotype/Genotype Correlations in Movement Disorders

StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Record History

The 50 most recent of 350 record versions are accounted for below. See every version on ClinicalTrials.gov ↗

  1. Re-verified, no change to tracked fields
  2. Re-verified, no change to tracked fields
  3. Eligibility criteria expanded, about 13 words Secondary endpoints: details revised at 3 of 5 entries · Study description expanded, about 6 words Show 2 more changesShow less
    • Secondary endpoints: details revised at 3 of 5 entries
    • Study description expanded, about 6 words
  4. 34 versions Re-verified since Mar 29, 2025, no change to tracked fieldsv314-v347
  5. Study arms: 1 to 3v313
  6. 12 versions Re-verified since Sep 7, 2024, no change to tracked fieldsv301-v312
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this protocol is to identify families with inherited movement disorders and evaluate disease manifestations to establish an accurate clinical diagnosis by using newest technological advances and investigate the underlying molecular mechanisms. Studies of inherited movement disorders in large families with good genealogical records are especially valuable. Patients with diseases of known molecular basis will be genotyped in order to investigate phenotype/genotype correlation. Patients with disease of unknown or incomplete genetic characterization will be studied with a hope of contributing to the identification of specific disease-causing genes and genetic mechanisms responsible for a specific disorder.
Trial Details
NCT Number NCT00018889
Lead Sponsor National Institute of Neurological Disorders and Stroke (NINDS)
Conditions Movement Disorder
Enrollment 2,500 participants
Start Date
Updated on ClinicalTrials.gov