Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIV

StatusRecruiting
PhaseNot specified
Started

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Record History

The 50 most recent of 385 record versions are accounted for below. See every version on ClinicalTrials.gov ↗

  1. Re-verified, no change to tracked fields
  2. Re-verified, no change to tracked fields
  3. Re-verified, no change to tracked fields
  4. New version filed on ClinicalTrials.gov
  5. 38 versions Re-verified since Nov 7, 2025, no change to tracked fieldsv344-v381
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  1. Enrollment target: 2400 to 2419v343
  2. 7 versions Re-verified since Jul 31, 2025, no change to tracked fieldsv336-v342
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
We are studying virologic and/or immunologic parameters of HIV infection and other infectious or non-infectious immune deficiency diseases in order to better understand the pathogenesis of HIV. Because of the lack of an adequate animal model it is generally necessary to utilize human peripheral blood cells for studying aspects of either in vivo or in vitro HIV infection. We wish to be able to continue to elucidate many pathogenic aspects of HIV infection in relation to other infectious or non-infectious immune regulation and dysregulation using human peripheral blood mononuclear cells as a model.
Trial Details
NCT Number NCT00001281
Lead Sponsor National Institute of Allergy and Infectious Diseases (NIAID)
Collaborators: Medstar Health Research Institute
Conditions
(from sponsor)		 HIV, Immunodeficiencies, Infectious Diseases
Related terms Communicable Diseases, Immunologic Deficiency Syndromes
Enrollment 2,419 participants
Start Date
Updated on ClinicalTrials.gov