Sponsor pipeline

PYC Therapeutics clinical trial pipeline

Data updated daily from ClinicalTrials.gov, last refresh 2026-10-16

What changed in the last 30 days

1 trial changed in the last 30 days: 0 stopped, 1 with a notable change, 0 with minor changes only.

Stopped: an ongoing trial was terminated, suspended or withdrawn.
Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Minor: routine progress and housekeeping, such as sites added or enrollment closed.

Phase 1		2
Phase 1/2		2

Not charted: 1 active trial with no phase listed on ClinicalTrials.gov (typically behavioural, device, procedure and observational studies).

NCT ID	Title	Condition	Status	Updated
Phase 1/2
NCT06970106	Safety of Single and Repeat Dose of PYC-001 Eye Injections in People With Autosomal…	OPA1 Gene Mutation	Recruiting	2026-06-29
NCT06852963	A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001…	Retinitis Pigmentosa 11	Active, Not Recruiting	2026-05-29
Phase 1
NCT06714006	Phase 1 Study to Evaluate the Safety and Tolerability of Intravenously Administered…	Autosomal Dominant Polycystic Kidney Disease (ADPKD)	Recruiting	2026-07-27
NCT06461286	SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew)	OPA1 Gene Mutation	Active, Not Recruiting	2026-09-17
Not specified
NCT05573984	Natural History of PRPF31 Mutation-Associated Retinal Dystrophy	Retinitis Pigmentosa	Active, Not Recruiting	2026-04-13

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