Drug Pipeline

VRC07-523LS Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
9
Active Studies
6
Recruiting
3
Top Sponsors
7
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-30 NCT06508749
The Tatelo Plus Study
date change Primary completion moved earlier: 2027-11-05 -> 2027-09-03
2026-05-30 NCT06508749
The Tatelo Plus Study
date change Completion moved earlier: 2028-04-21 -> 2028-02-18
2026-05-30 NCT04983030
Safety, Immunogenicity, Efficacy of Ad26.Mos4.HIV, MVA-BN-HIV and PGT121, PGDM1400, and…
Trial completed
2026-05-30 NCT04983030
Safety, Immunogenicity, Efficacy of Ad26.Mos4.HIV, MVA-BN-HIV and PGT121, PGDM1400, and…
Enrollment reduced: 36 -> 28 participants
2026-05-30 NCT04983030
Safety, Immunogenicity, Efficacy of Ad26.Mos4.HIV, MVA-BN-HIV and PGT121, PGDM1400, and…
date change Completion moved earlier: 2026-04-30 -> 2026-02-23
2026-05-29 NCT07215468
HIV-1 Virologic Suppression With TMB-365 and TMB-380 Antibodies Study
overall status: "Recruiting" → "Active Not Recruiting"
2026-05-29 NCT07215468
HIV-1 Virologic Suppression With TMB-365 and TMB-380 Antibodies Study
Enrollment increased: 75 -> 88 participants
Active Studies by Phase
Phase 2
3
Phase 1/2
2
Phase 1
4
Active Trials
NCT IDTitleConditionStatus
Phase 2
NCT06812494 A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal… HIV Recruiting
NCT05719441 A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies… Acute HIV Infection Recruiting
NCT07215468 HIV-1 Virologic Suppression With TMB-365 and TMB-380 Antibodies Study HIV -1 Infection Active, Not Recruiting
Phase 1/2
NCT02140255 Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission HIV Infection Recruiting
NCT06508749 The Tatelo Plus Study HIV Recruiting
Phase 1
NCT07390955 A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult… HIV Recruiting
NCT06517693 Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With… HIV-1 Recruiting
NCT06987318 A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies… HIV-1-infection Not Yet Recruiting
NCT05890963 10E8.4/iMab Bispecific Antibody and VRC07-523LS Monoclonal Antibody in HIV-infected Adults HIV-1-infection Active, Not Recruiting
Sponsors Running VRC07-523LS Trials
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