Drug Pipeline

TNG462 Clinical Trials

Data updated daily from ClinicalTrials.gov — last refresh 2026-06-12
3
Active Studies
2
Recruiting
2
Top Sponsors
5
Changes, 30 Days
What Changed in the Last 30 Days
DetectedTrialChange
2026-05-27 NCT06188702
S095035 as a Single Agent and in Combination in Adult Participants With Advanced or…
overall status: "Recruiting" → "Active Not Recruiting"
2026-05-27 NCT06188702
S095035 as a Single Agent and in Combination in Adult Participants With Advanced or…
Enrollment reduced: 342 -> 60 participants
2026-05-27 NCT06188702
S095035 as a Single Agent and in Combination in Adult Participants With Advanced or…
Trial sites reduced: 35 -> 22 locations
2026-05-27 NCT06188702
S095035 as a Single Agent and in Combination in Adult Participants With Advanced or…
date change Primary completion moved earlier: 2031-10-31 -> 2027-05-01
2026-05-27 NCT06188702
S095035 as a Single Agent and in Combination in Adult Participants With Advanced or…
date change Completion moved earlier: 2031-10-31 -> 2027-05-01
Active Studies by Phase
Phase 1/2
3
Active Trials
NCT IDTitleConditionStatus
Phase 1/2
NCT05732831 Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors Locally Advanced Solid Tumor Recruiting
NCT06922591 Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC &… PDAC Recruiting
NCT06188702 S095035 as a Single Agent and in Combination in Adult Participants With Advanced or… MTAP-deleted Solid Tumors Active, Not Recruiting
Sponsors Running TNG462 Trials
Disease Areas
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