Healthy volunteers | Browse diseases and conditions

Persons with no known significant health problems who are recruited to participate in research to test a new drug, device, or intervention as controls for a patient group. MeSH definition

Active trials

Trials listed under a disease or condition are not repeated here. Showing the 25 most recently updated of 953 active trials.

Establishment of Biobank of Nasal Epithelium Samples From Healthy Volunteers Not Yet Recruiting · Not specified · National Institute of Allergy and Infectious Diseases (NIAID)
A Study of V118E in Healthy Participants (V118E-003) Active, Not Recruiting · Phase 1 · Merck Sharp & Dohme LLC
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Food Effect of JZP047 in Healthy Participants Active, Not Recruiting · Phase 1 · Jazz Pharmaceuticals
Modulation of Appetite Signaling Through Enterohormone Stimulation by DNF-10 Recruiting · Not applicable · Fytexia
Discovering Determinants of Food Intake by Application of Artificial Intelligence to Complex, High-Dimensional Data Not Yet Recruiting · Not specified · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Survey to Determine Incarcerated Persons' Views on Surrogate Decision Making Recruiting · Not specified · National Institutes of Health Clinical Center (CC)
Visual Attention, Object Recognition, and Eye Movements in Healthy Volunteers Recruiting · Not specified · National Eye Institute (NEI)
Dynamic Magnetic Resonance Imaging of Human Subarachnoid Space Using Intrathecal Gadolinium Contrast Not Yet Recruiting · Phase 1 · National Institute of Neurological Disorders and Stroke (NINDS)
A Study to Test a Single Dose of a New Tablet Formulation of TRTL-729 Recruiting · Phase 1 · Tortugas Neuroscience, Inc.
A Trial in Healthy Participants to Assess Drug Interaction Potential of BGB-43395 Recruiting · Phase 1 · BeOne Medicines
First-in-Human Evaluation of [11C]JMJ-129-d2 for PDE4D Imaging in Healthy Volunteers Recruiting · Phase 1 · National Institute of Mental Health (NIMH)
Building Core Competencies of Taiwanese Care Food Specialists: Curriculum Design and Outcome Assessment Recruiting · Not applicable · Chang Gung Memorial Hospital
Phase 1 Study in Healthy Adults to See How Sevabertinib Changes Metformin Levels in the Body Recruiting · Phase 1 · Bayer
Positron Emission Tomography (PET) Imaging of Reactive Oxygen and Nitrogen Species: Human Observation of Retention and Safety of [18F]-Fluoroedaravone Not Yet Recruiting · Early Phase 1 · St. Jude Children's Research Hospital
Safety, Tolerability, PK, and PD of TGM-148 in Healthy Participants Recruiting · Phase 1 · Tangram Therapeutics Plc
A Single Ascending Dose Study of DTI-117 Given Intramuscularly in Healthy Participants. Not Yet Recruiting · Phase 1 · Dignify Therapeutics
A Phase 1 Multiple Dose Trial in Healthy Adult Participants to Evaluate the Safety, Tolerability, Drug-Drug Interactions, and Pharmacokinetics of TBD11 Recruiting · Phase 1 · Gates Medical Research Institute
Assessing the Effect of a Proton Pump Inhibitor on the Pharmacokinetics of DZD8586 in Healthy Participants (TAI-SHAN21) Not Yet Recruiting · Phase 1 · Dizal Pharmaceuticals
Comparative Effect of Training Methods to Reduce Forefoot Loading in Carbon Fiber Custom Dynamic Orthoses Recruiting · Not applicable · Jason Wilken
Sample Collection From Healthy Volunteers for Assay Optimization Recruiting · Not specified · National Institute of Allergy and Infectious Diseases (NIAID)
A Study to Learn How Different Preparations of Osivelotor Taste and Enter the Blood With Food or Liquids or With an Antacid in Healthy Adults Recruiting · Phase 1 · Pfizer
Role of Metal Ion Transporter ZIP8 in Alcohol-Related Behaviors Recruiting · Phase 1 · National Institute on Alcohol Abuse and Alcoholism (NIAAA)
A Study Testing the Safety and Effects of FB102 in Healthy Volunteers Recruiting · Phase 1 · Forte Biosciences, Inc.
An Open-label DDI Study to Investigate the Effect of Rilzabrutinib on P-gp, BCRP, OATP1B1 and OATP1B3 Inhibition Active, Not Recruiting · Phase 1 · Sanofi
A Study of Single and Multiple Subcutaneous or Intravenous Doses of ADX-001 in Healthy Adults to Assess Safety, Effects, and Immune Response Recruiting · Phase 1 · Adaxion Therapeutics