The Microbiome in Uveitis and Pediatric Inflammatory Diseases

Study acronym: MUMIP
StatusNot Yet Recruiting
PhaseNot specified
Started

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Record History

  1. Study First Submitted
Chronic, noninfectious uveitis in children, associated with various systemic inflammatory diseases, carries a high risk of vision loss. Intestinal dysbiosis and the translocation of bacterial peptidoglycans (PG) that activate innate receptors recognizing PG could represent a common initiating mechanism, independent of the underlying disease. Studying these biological signatures in comparative cohorts could lead to a better understanding of the onset of uveitis and the development of targeted diagnostic and therapeutic strategies.
Trial Details
NCT Number NCT07885501
Lead Sponsor Assistance Publique - Hôpitaux de Paris
Conditions
(from sponsor)
Noninfectious Uveitis
Enrollment 500 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov