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A Study to Learn About the Study Medicine Called Ponsegromab in Adults With Lung Cancer-Associated Significant Body Weight Loss

StatusNot Yet Recruiting
PhasePhase 1
SponsorPfizer
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 3 months later Feb 2, 2028 → May 5, 2028
See other at-risk trials from Pfizer

Record History

See every version on ClinicalTrials.gov ↗

  1. Trial sites expanded: 0 → 7 locations
    • Primary completion date: May 5, 2028 to May 6, 2028
    • Eligibility criteria expanded, about 27 words
    • Secondary endpoints: details revised at 1 of 5 entries
  2. Start date: Jul 22, 2026 to Oct 23, 2026v2 Show 5 more changesShow less
    • Primary completion pushed from Feb 2, 2028 to May 5, 2028
    • Study completion pushed from Mar 29, 2029 to Jul 1, 2029
    • Eligibility criteria expanded, about 22 words
    • Secondary endpoints revised (5)
    • Study title expanded, about 1 word
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Study to investigate the effect of ponsegromab on skeletal muscle mass and physical function in adult participants with non-small cell lung cancer associated cachexia.
Trial Details
NCT Number NCT07663630
Lead Sponsor Pfizer
Conditions
(from sponsor)		 Non-small Cell Lung Cancer (NSCLC), Cachexia
Related terms Anorexia, Cachexia, Carcinoma, Non-Small-Cell Lung, Fatigue, Neoplasms, Weight Loss
Enrollment 80 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov