MinorPrimary completion pushed from Feb 22, 2026 to Apr 6, 2026
Eligibility criteria expanded, about 23 words
Secondary endpoints: details revised at 14 of 14 entries
Publications: details revised at 36 of 51 entries
MinorSecondary endpoints: 37 to 14v19
MinorStudy completion date: Feb 22, 2026 to Dec 31, 2026v18
MinorTrial status: Recruiting to Active, Not Recruiting
Primary and study completion dates: Dec 31, 2025 to Feb 22, 2026
Site details revised at 2 of 2 sites
v17
2 versionsRe-verified since Jul 26, 2024, no change to tracked fieldsv15-v16
Show 13 earlier versionsHide 13 earlier versions
MinorStudy description shortened, about 6 wordsv14
NotableTrial status: Not Yet Recruiting to Recruiting
Start date changed from estimate of Jun 26, 2023 to Jul 18, 2023
Site details revised at 2 of 2 sites
v13
MinorPrimary and study completion dates: Sep 30, 2025 to Dec 31, 2025
Start date: Jun 19, 2023 to Jun 26, 2023
v12
MinorSecondary endpoints: 32 to 37
Study description shortened, about 36 words
v11
NotableStart date: May 15, 2023 to Jun 19, 2023v10
MinorStart date: May 8, 2023 to May 15, 2023v9
NotableStart date: Apr 3, 2023 to May 8, 2023v8
NotableStart date: Mar 1, 2023 to Apr 3, 2023v7
MinorPrimary and study completion dates: Aug 31, 2025 to Sep 30, 2025v6Show 4 more changesShow less
Eligibility criteria expanded, about 107 words
Secondary endpoints: 26 to 32
Study description shortened, about 12 words
Study title expanded, about 1 word
NotableStart date: Jan 15, 2023 to Mar 1, 2023v5
NotableStart date: Nov 1, 2022 to Jan 15, 2023v4
NotableStart date: Aug 1, 2022 to Nov 1, 2022v3
MinorSecondary endpoints: 25 to 26v2
Study First Submitted
Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The purpose of the present study is to utilize Multiphase Optimization Strategy (MOST)1 to test four social support and mindfulness components (e-coaching, buddy, general mindfulness training, and MVPA-specific mindfulness training) in a 12-week mHealth moderate to vigorous intensity physical activity (MVPA) intervention in a sample of young adult cancer survivors (YACS), to improve quality of life (QOL) and decrease adverse effects and symptom burden.
PRIMARY AIM To identify which components from four mHealth components under consideration for inclusion meaningfully contribute to improvements in MVPA at 12 and 24 weeks
SECONDARY AIM To examine how changes in MVPA, as a result of Opt2Move components, may influence additional health behaviors and outcomes including: a) symptom burden (i.e. fatigue, depression, anxiety); b) time spent in other activity intensities (i.e. light, sedentary time); and c) sleep duration and quality
THIRD AIM To examine potential mediators (i.e. adherence, psychosocial factors such as post-traumatic growth, self-compassion, self-efficacy, and goal setting) and moderators (cancer type, age, gender) of the four intervention components on MVPA.
Trial Details
NCT Number
NCT05375162
Lead Sponsor
Northwestern University Collaborators: National Cancer Institute (NCI), Wake Forest University Health Sciences