University of Alabama at Birmingham clinical trial pipeline

45 trials changed in the last 30 days: 7 stopped, 22 with notable changes, 16 with minor changes only.

1. Stopped

   Intranasal Delivery of Octreotide · Diabetic Macular Edema

   Withdrawn before enrolling

   Sponsor's reason: Project terminated due to loss of sponsor funding following the dissolution of AMD Opti.

   Also in this update: Primary completion date changed from estimate of Dec 2027 to Oct 8, 2026

   University of Alabama at Birmingham·Phase 1· NCT06881888· Registry history of NCT06881888 on ClinicalTrials.gov (opens the registry)

   Updated Oct 13, 2026

2. Stopped

   Integrative Liver-Targeted Therapy for Diabetic Macular Edema…Integrative Liver-Targeted Therapy for Diabetic Macular Edema: Using "Tauroursodeoxycholate" or Traditional Chinese Medicine

   Withdrawn before enrolling

   Sponsor's reason: The study was terminated due to additional regulatory requirements that could not be completed within the established academic timeline. As a result, continuation of the study was not feasible.

   University of Alabama at Birmingham·Phase 2· NCT07457632· Registry history of NCT07457632 on ClinicalTrials.gov (opens the registry)

   Updated Oct 9, 2026

3. Stopped

   ProAgio in Advanced/Metastatic Colorectal Cancer

   Recruitment suspended

   Sponsor's reason: temporary suspended

   University of Alabama at Birmingham·Phase 1· NCT06867822· Registry history of NCT06867822 on ClinicalTrials.gov (opens the registry)

   Updated Oct 2, 2026

4. Stopped

   Release Kinetics of rhBMP-2 Using E-PRF as an Autologous Carrier…Release Kinetics of rhBMP-2 Using E-PRF as an Autologous Carrier: An In Vitro Analysis

   Withdrawn before enrolling

   Sponsor's reason: The study was stopped due to the funding issues.

   University of Alabama at Birmingham·Not specified· NCT04670965· Registry history of NCT04670965 on ClinicalTrials.gov (opens the registry)

   Updated Sep 30, 2026

5. Stopped

   Comparative Efficacy of Saccadic and Biofeedback Training in…Comparative Efficacy of Saccadic and Biofeedback Training in Homonymous Hemianopia

   Trial status changed: Not Yet Recruiting → Suspended

   Sponsor's reason: funding

   Also in this update: Primary and study completion pushed from Dec 2026 to Dec 2027

   University of Alabama at Birmingham·Not applicable· NCT06638619· Registry history of NCT06638619 on ClinicalTrials.gov (opens the registry)

   Updated Sep 25, 2026

6. Stopped

   Making Intergenerational Connections Through Arts

   Trial status changed: Recruiting → Withdrawn

   Sponsor's reason: no participants enrolled

   Also in this update: Primary completion date changed from estimate of Aug 31, 2029 to Aug 31, 2026

   University of Alabama at Birmingham·Not specified· NCT05986149· Registry history of NCT05986149 on ClinicalTrials.gov (opens the registry)

   Updated Sep 25, 2026

7. Stopped

   Sensory Filtering in the Human Basal Ganglia as a Mechanism of…Sensory Filtering in the Human Basal Ganglia as a Mechanism of Parkinson's Disease

   Recruitment suspended

   Sponsor's reason: Suspending since no longer working participants at this time or enrolling new ones.

   University of Alabama at Birmingham·Not specified· NCT05482126· Registry history of NCT05482126 on ClinicalTrials.gov (opens the registry)

   Updated Sep 24, 2026

8. Notable

   PAOO · Orthodontic Molar Protraction With and Without Adjunctive…PAOO · Orthodontic Molar Protraction With and Without Adjunctive Surgery

   Primary completion pushed from Dec 30, 2027 to Dec 30, 2028

   Also in this update: Study completion pushed from Dec 30, 2028 to Dec 30, 2029

   University of Alabama at Birmingham·Not applicable· NCT03794726· Registry history of NCT03794726 on ClinicalTrials.gov (opens the registry)

   Updated Oct 15, 2026

9. Notable

   RAD 1802 · Five Fraction Stereotactic Body Radiotherapy for Early…RAD 1802 · Five Fraction Stereotactic Body Radiotherapy for Early Stage Breast Cancer Patients Eligible for Post-Operative Accelerated Partial Breast Irradiation (APBI)

   Primary completion pushed from Dec 2027 to Dec 1, 2029

   Also in this update: Study completion pushed from Dec 2028 to Dec 1, 2029

   University of Alabama at Birmingham·Not applicable· NCT03643861· Registry history of NCT03643861 on ClinicalTrials.gov (opens the registry)

   Updated Oct 13, 2026

10. Notable

    Bony Overlap Following Use of the Inferior Border Saw for the 'Low…Bony Overlap Following Use of the Inferior Border Saw for the 'Low and Short' Sagittal Split: A Split-Mouth Study

    Primary completion pushed from Sep 2026 to May 2027

    Also in this update: Study completion pushed from Feb 2027 to Aug 2027

    University of Alabama at Birmingham·Not applicable· NCT07104656· Registry history of NCT07104656 on ClinicalTrials.gov (opens the registry)

    Updated Oct 8, 2026

11. Notable

    MASTER-2 · Sequential Therapy in Multiple Myeloma Guided by MRD…MASTER-2 · Sequential Therapy in Multiple Myeloma Guided by MRD Assessments

    Primary completion pushed from Dec 2027 to Sep 2028

    Also in this update: Enrollment closed, study ongoing

    University of Alabama at Birmingham·Phase 2· NCT05231629· Registry history of NCT05231629 on ClinicalTrials.gov (opens the registry)

    Updated Sep 22, 2026

12. Notable

    GENESIS · Genotype Guided - Natriuretic Peptides…GENESIS · Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study

    Primary completion pushed from Sep 30, 2026 to Apr 1, 2027

    University of Alabama at Birmingham·Not applicable· NCT05216042· Registry history of NCT05216042 on ClinicalTrials.gov (opens the registry)

    Updated Oct 5, 2026

13. Notable

    APNeA · Application to Predict Neonatal Apnea With Bradycardia

    Primary completion pushed from Dec 31, 2026 to Dec 31, 2027

    Also in this update: Recruitment opened; Study completion pushed from Dec 31, 2027 to Dec 31, 2028

    University of Alabama at Birmingham·Not applicable· NCT06852053· Registry history of NCT06852053 on ClinicalTrials.gov (opens the registry)

    Updated Oct 2, 2026

14. Notable

    Speed of Processing Training to Improve Cognitive Functioning and…Speed of Processing Training to Improve Cognitive Functioning and Driving Performance in Head and Neck Cancer Survivors

    Primary completion pushed from Sep 2028 to Sep 2029

    University of Alabama at Birmingham·Not applicable· NCT07740616· Registry history of NCT07740616 on ClinicalTrials.gov (opens the registry)

    Updated Oct 2, 2026

15. Notable

    Acceptance and Commitment Therapy for Religious OCD

    Primary and study completion pushed from Sep 1, 2026 to Mar 1, 2027

    University of Alabama at Birmingham·Not applicable· NCT06647589· Registry history of NCT06647589 on ClinicalTrials.gov (opens the registry)

    Updated Sep 28, 2026

16. Notable

    Use of Plastic Bags to Prevent Neonatal Hypothermia-Part I

    Primary and study completion pushed from Aug 15, 2026 to Sep 22, 2027

    University of Alabama at Birmingham·Not applicable· NCT01604317· Registry history of NCT01604317 on ClinicalTrials.gov (opens the registry)

    Updated Sep 25, 2026

17. Notable

    Interrupted Time-Series Pilot Trial of LGBTQ-Affirming Cognitive…Interrupted Time-Series Pilot Trial of LGBTQ-Affirming Cognitive Processing Therapy for Interpersonal and Developmental Trauma

    Primary endpoint(s) modified

    University of Alabama at Birmingham·Not applicable· NCT07863817· Registry history of NCT07863817 on ClinicalTrials.gov (opens the registry)

    Updated Oct 15, 2026

18. Notable

    Pirfenidone in Acute Pancreatitis

    Primary endpoint(s) modified

    Also in this update: Final enrollment: 1 participants — 2% of the 60 planned; Results posted: Sep 23, 2026

    University of Alabama at Birmingham·Phase 1/2· NCT05350371· Registry history of NCT05350371 on ClinicalTrials.gov (opens the registry)

    Updated Sep 23, 2026

19. Notable

    INSPIRE · INtegrating Systematic PatIent-Reported Evaluations in…INSPIRE · INtegrating Systematic PatIent-Reported Evaluations in Multi-Disciplinary Tumor Boards: The INSPIRE Study

    Recruitment opened

    University of Alabama at Birmingham·Not applicable· NCT07671937· Registry history of NCT07671937 on ClinicalTrials.gov (opens the registry)

    Updated Oct 7, 2026

20. Notable

    B-CARE · Bundled Intervention to End Opioid Overdoses

    Recruitment opened

    University of Alabama at Birmingham·Phase 4· NCT07485335· Registry history of NCT07485335 on ClinicalTrials.gov (opens the registry)

    Updated Oct 2, 2026

• Stopped: an ongoing trial was terminated, suspended or withdrawn.
• Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
• Minor: routine progress and housekeeping, such as sites added or enrollment closed.